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Lyclear Dermal Cream is used to treat scabies and crab lice.. Permethrin belongs to a group of medicines called the pyrethroids which are anti-parasitic agents.
Lyclear Dermal Cream is for external use only.
Avoid contact with the eyes. In the event of eye contamination, rinse with water immediately.
Ensure the skin is clean, dry and cool. Do not take a hot bath immediately before treatment.
You should make sure that you carefully read all product packaging and labels prior to use
Permethrin (5% w/w). It also contains coconut oil, glyceryl monostearate, macrogol cetyl ether, cetomacrogol 1000, isopropyl myristate, lanolin alcohols/liquid paraffin mixture, butylated hydroxytoluene (E321) glycerol, formaldehyde solution, carbomer, sodium hydroxide and purified water.
Like all medicines, Lyclear Dermal Cream can have side-effects, although these are rare and usually mild.
Occasionally burning or stinging of the skin occurs, but it is usually slight and passes quickly.
Treatment of scabies may result in continued or increased irritation for a short while. This may show as redness of the skin, a rash or itching.
You might find that the itching you have been experiencing continues for up to 4 weeks after the treatment with Lyclear Dermal Cream. This is normal and is caused by an allergic reaction to the dead scabies mites. It is not a sign that the treatment has failed. If you notice any side-effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Product information leaflet:
http://emc.medicines.org.uk/medicine/10439/SPC/Lyclear Dermal Cream/
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Permethrin, Medical Grade 5.0% w/w (Cis/Trans Isomer 25/75)
Cream for topical application
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Treatment of scabies
Lyclear Dermal Cream is suitable for use by adults and children of 2 months of age and above.
Lyclear Dermal Cream is also suitable for use by the elderly.
Lyclear Dermal Cream should be applied to clean, dry, cool skin. If the patient has taken a warm bath prior to treatment the skin should be allowed to cool before the cream is applied.
Lyclear Dermal Cream is a vanishing cream and when rubbed gently into the skin it will disappear. Therefore, there is no need to continue to apply cream to the skin until it remains detectable on the surface.
Older children should be supervised by an adult when applying to ensure that a thorough treatment is administered.
The whole body should be washed thoroughly 8 – 12 hours after treatment.
Use in adults and children over 2 months
In view of the great individual variability in body area and skin types precise recommendations are not possible.
For adults and children over 12 years of age, up to a 30 g tube may be used as a single application. A few adults may need to use more than one tube to ensure total body coverage, but not more than two tubes (60 g in total) should be used for a single application.
For children 12 years and under, the following table indicates the approximate amount of cream to be used as a single application. These drug recommendations are based on the use of a 30 g tube.
Children aged:
2 months to 1 year - Up to 1/8 of a tube
1-5 years - Up to ¼ of a tube
6-12 years - Up to ½ of a tube
In cases where the head, neck, scalp and ears are treated (see below) the dosage may be increased to ensure total body coverage.
In adults and children over 2 years of age Lyclear Dermal Cream should be applied to the whole body excluding the head paying particular attention to the areas between the fingers and toes, wrists, axillae, external genitalia, buttocks and under finger and toe nails. In women, the whole body application should include the breasts.
During the treatment period, Lyclear Dermal Cream should be re-applied to the hands if they are washed with soap and water.
Children between 2 months and 2 years should be treated under medical supervision. Lyclear Dermal Cream should be applied over the whole body as directed for adults and children over 2 years, but should include the palms, soles, face, neck, scalp and ears. Care must be taken to avoid the vicinity of the mouth where it could be licked off, and areas close to the eyes.
Approximately 90% of individuals are cured with a single application of cream. If necessary, a second application may be given not less than 7 days after the initial application, if there are no signs of the original lesions healing or if new lesions are present.
Use in the Elderly
In the elderly Lyclear Dermal Cream should be used as directed for adults and children over 12 years but should also include the head, neck, scalp and ears. Care must be taken to avoid applying Lyclear Dermal Cream to areas close to the eyes.
Treatment of crab lice
The elderly
The elderly should be treated only on the advice of a doctor or a health professional.
Adults 18 years and over
Sufficient cream should be applied to cover the pubic region, peri-anal (around the anus), inner thighs down to the knees and any hair that grows up from the pubic area to the chest/stomach.
One (30 g) tube is more than sufficient to treat one hairy adult. It is recommended that up to a third of a tube is used to treat the pubic region, peri-anal region, thighs, stomach and chest. Not more than two thirds of the tube should be needed for complete treatment.
For relatively hair-free individuals proportionately less cream will be required.
The cream should be left on the skin for 24 hours. The treatment areas should then be thoroughly washed.
Any facial hair (beards, moustaches) and eyelashes should be checked for the presence of live lice and eggs. Cream should be applied to any facial hair, carefully avoiding eyes. If live lice or eggs are found on the eyelashes they should be removed carefully using tweezers. Cream should not be applied to the eyelashes because the cream can cause moderate eye irritation.
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Lyclear Dermal Cream is contraindicated in subjects with known hypersensitivity to the product, its components, other pyrethroids or pyrethrins.
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Lyclear Dermal Cream is for external use only and should be kept out of reach of children.
Permethrin is not an eye irritant but contact of Lyclear Dermal Cream with the eyes should be avoided because the cream itself may cause marked irritation.
In the event of inadvertent eye contamination, the affected area should be rinsed immediately with plenty of water or, if readily available, normal saline.
Nursing staff who routinely apply Lyclear Dermal Cream may wish to wear gloves to avoid any possible irritation to the hands.
There is an increasing body of data specifically relating to the use of Lyclear Dermal Cream for the treatment of scabies in the elderly and in view of these data it is considered that there is no need for any special precautions for use in this age group.
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