Dectomax Sheep/Cattle Injection 50ml

Presentation

Dectomax injectable solution is a ready-to-use, colourless to pale yellow, sterile solution containing 1% w/v doramectin (10 mg/ml).
Uses

Dectomax injectable solution is a highly active broad spectrum endectocide for parenteral administration to cattle and sheep. It contains doramectin, a novel fermentation-derived avermectin discovered by Pfizer.

Cattle

Dectomax injectable solution is indicated for the treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, eye-worms, warbles, lice and mange mites in cattle.

Gastrointestinal roundworms (adults and fourth stage larvae)

Ostertagia ostertagi (incl. inhibited larvae)

O. lyrata1

Haemonchus placei

Trichostrongylus axei

T. colubriformis

Cooperia oncophora

C.pectinata1

C.punctata

C.surnabada (syn. mcmasteri)

Nematodirus spathiger1

Bunostomum phlebotomum1

Strongyloides papillosus1

Oesophagostomum radiatum

Trichuris spp.1

Lungworms (adults and fourth stage larvae)

Dictyocaulus viviparus

Eyeworms (adults)

Thelazia spp.

Warbles (parasitic stages)

Hypoderma bovis, H.lineatum

Sucking lice

Haematopinus eurysternus. Linognathus vituli, Solenopotes capillatus

Mange mites

Psoroptes bovis, Sarcoptes scabiei

1 adults only

Dectomax injectable solution may also be used as an aid in the control of Nematodirus helvetianus of biting lice (Damalinia bovis), and of the mange mite Chorioptes bovis.

The pharmacokinetics of Dectomax injectable solution allow protection of cattle against infection or re-infection with the following parasites for the period indicated:

Species
Days

Bunostomum phlebotomum
22

Cooperia oncophora
21

Dictyocaulus viviparus
35

Haemonchus placei
28

Linognathus vituli
28

Oesophagostomum radiatum
21

Ostertagia ostertagi
35

Psoroptes bovis
42

Trichostrongylus axei
28

To obtain optimal benefit from the action of Dectomax injectable solution, it is recommended that cattle which are set-stocked should be treated at turnout and eight weeks later. Studies have demonstrated that, used in this way, Dectomax will reduce the build-up of infective larvae on pasture and can protect animals from parasitic gastro-enteritis and parasitic bronchitis throughout the grazing season. To obtain these results, all animals must be included in the programme and untreated cattle must not be introduced on the pasture. Treated cattle should always be monitored according to good husbandry practices. Treatment with Dectomax injectable solution at turnout and eight weeks later of cattle set-stocked for the grazing season can protect against clinical disease caused by lungworm and may allow the development of naturally acquired immunity. However, due to the unpredictable nature of lungworm epidemiology, clinical signs of lungworm disease may on occasion be seen, particularly towards the end of the grazing season, if the season is long. If this occurs, cattle should be further treated with an anthelmintic effective against lungworm.

Sheep

Dectomax injectable solution is indicated for the effective treatment and control of Psoroptes ovis (sheep scab mite) and Nematodirus battus at the recommended dose rate of 300 mcg/kg bodyweight (1 ml/33 kg).

Dectomax injectable solution is indicated for the treatment of the following species of gastrointestinal roundworms, lungworms and nasal bots in sheep at the recommended dose rate of 200 mcg per kilogram bodyweight:

Gastrointestinal roundworms (Adults and fourth stage larvae(L4) unless otherwise indicated)

Chabertia ovina (adults only)

Cooperia curticei (L4 only)

C. oncophora

Gaigeria pachyscelis

Haemonchus contortus

Nematodirus battus (L4 only)1

Oesophagostomum columbianum

Ostertagia (Teladorsagia) circumcincta *

Strongyloides papillosus

Trichostrongylus axei

T. colubriformis

T. vitrinus

Trichuris spp. (adults only)

* Inhibited larval stages (L4) including strains that are benzimidazole resistant, are also controlled.

1 For effective treatment and control of both adults and L4 larvae of Nematodirus battus a dose rate of 300 mcg/kg is required.

Lungworm

Dictyocaulus filaria (adults only)

Nasal bots (1st, 2nd and 3rd instar larvae)

Oestrus ovis

Dosage and administration

Dectomax is a clear, sterile solution. In common with other non-aqueous formulations the product contains no antimicrobial preservative. Dry, sterile equipment and aseptic procedures should therefore be used when administering Dectomax to animals. Swab the septum before removing the dose. When the temperature of the formulation is below 5°C, syringeability may be improved by gently warming the injecting equipment and product.

When treating groups of animals, use only the Dectomax automatic dosing device and vented draw-off apparatus. When treating individual animals syringes must be filled from the vial through a dry, sterile draw-off needle that has been placed in the vial stopper. Vial stoppers must not be broached more than 20 times.

Cattle

Administer Dectomax injectable solution at a dosage of 200 mcg doramectin per kilogram of bodyweight by the subcutaneous route. Each ml contains 10 mg of doramectin, sufficient to treat 50 kg of bodyweight. Each injection should be made into the neck region using a dry sterile 16 to 18 gauge needle, 15 mm in length.

Sheep

For the treatment and control of Psoroptes ovis (sheep scab mite) and Nematodirus battus, a dosage of 300 mcg/kg bodyweight should be used by the intramuscular route. Each ml contains 10 mg of doramectin, 1.0 ml is sufficient to treat 33 kg of bodyweight

In adult sheep each intramuscular injection should be made using a dry sterile 16 to 18 gauge needle, 25 mm in length. (For the treatment of individual sheep a disposable 2 ml syringe calibrated in increments of 0.1 ml should be used).

Suggested dose rates for Psoroptes ovis (sheep scab mite) and Nematodirus battus: 1 ml/33 kg bodyweight (300 mcg/kg). Sheep over 16 kg bodyweight:

Bodyweight
Dose

17 - 25 kg
0.75 ml

26 - 33 kg
1.0 ml

34 - 41 kg
1.25 ml

42 - 50 kg
1.5 ml

51 - 58 kg
1.75 ml

59 - 66 kg
2.0 ml

67 - 74 kg
2.25 ml

75 - 83 kg
2.5 ml

84 - 91 kg
2.75 ml

92 - 99 kg
3.0 ml

In young lambs of less than 16 kg bodyweight seek veterinary advice regarding the use of appropriate sized needles and of 1 ml disposable syringes graduated in increments of 0.1 ml or less. Suggested dose rates at 1 ml/33 kg bodyweight (300 mcg/kg) in young lambs:

Bodyweight
Dose

Less than 4 kg
0.1 ml

5 - 6 kg
0.2 ml

7 - 10 kg
0.3 ml

11 - 13 kg
0.4 ml

14 - 16 kg
0.5 ml

For treatment of gastro-intestinal roundworms, lungworms and nasal bots, administer Dectomax injectable solution once at a dosage of 200 mcg doramectin per kilogram of bodyweight by the intramuscular route. Each ml contains 10 mg of doramectin, sufficient to treat 50 kg of bodyweight.

Contra-indications, warnings, etc

Animals must not be slaughtered for human consumption during treatment.

Cattle

Cattle may be slaughtered for human consumption only after 56 days from the last treatment. Not for use in lactating cows producing milk for human consumption. Do not use in dry dairy cows including pregnant dairy heifers within 60 days prior to calving.

Sheep

Sheep may be slaughtered for human consumption only after 70 days from the last treatment, therefore veterinary advice should be sought regarding treatment for infected sheep that are within 70 days of slaughter. NOT FOR USE IN DAIRY EWES. Can be used in pregnant non-dairy ewes.

Assess bodyweight as accurately as possible before calculating dosage. Administer the calculated dose accurately, particularly when treating young lambs.

Dectomax injectable solution is registered for use in cattle and sheep. It should not be used in dogs, as severe adverse reactions may occur. In common with other avermectins, certain breeds of dog, such as collies, are especially sensitive to doramectin and particular care should be taken to avoid accidental consumption of the product.

Operator warnings

Do not eat, drink or smoke while handling the product. Wash hands after use.

Take care to avoid accidental self administration - seek medical attention should any specific signs be noticed

Advice to Medical Practitioners: In cases of accidental self injection specific symptoms have rarely been observed and therefore any cases should be treated symptomatically.

Disposal advice

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

EXTREMELY DANGEROUS to fish and aquatic life. Do not contaminate ponds, waterways or ditches with the product or used container.
Pharmaceutical precautions

Store below 30°C. Do not freeze or refrigerate. Protect from direct sunlight. Following withdrawal of the first dose, use the product within 6 months. Dispose of unused material safely.

For animal treatment only.

Keept out of reach of children.

Legal category

POM-VPS (previously PML)
Packaging Quantities

Multi-dose vials of 50 ml, 200 ml and 500ml.
Further information

Sheep scab (caused by Psoroptes ovis) is an extremely contagious disease. In view of scab control requirements in the UK, treatment with 300 mcg doramectin per kg bodyweight is recommended to ensure elimination of all mites. In addition, where possible, adequate bio-security measures should be implemented to prevent re-infestation. Ensure that all sheep which have been in contact with infested sheep are treated. After treatment, contact between treated infected and untreated uninfected flocks must be avoided for at least 14 days. When used for scab treatment in sheep, Dectomax injectable solution is also effective against certain gastro-intestinal roundworms, and this treatment may form part of a worm control programme in the flock.

Anthelmintics class

3-AV
Marketing authorisation number

Vm 00057/4094.