Dectomax Pour On for Cattle | Doramectin Cattle Wormer-Hyperdrug

Presentation
0.5% pour-on solution (5 mg/ml) for cattle.

Product description
Dectomax Pour-On for Cattle is a ready-to-use, colourless, solution containing 0.5% w/v doramectin (5 mg/ml). It is formulated to deliver the recommended dosage of 500 mcg/kg bodyweight when given by topical administration at the rate of 1 ml/10 kg bodyweight.

Product characteristics
Dectomax Pour-On for Cattle is a highly active broad spectrum parasiticide for topical administration to cattle. It contains doramectin, a novel fermentation-derived compound discovered by Pfizer. Doramectin is isolated from fermentation of selected strains derived from the soil organism Streptomyces avermitilis.
A primary mode of action of doramectin is to modulate chloride ion channel activity in the nervous system of nematodes and arthropods. Doramectin binds to receptors that increase membrane permeability to chloride ions. This inhibits the electrical activity of nerve cells in nematodes and muscle cells in arthropods and causes paralysis and death of the parasites. In mammals the neuronal receptors to which doramectin binds are localised within the central nervous system (CNS), a site reached by only negligible concentrations of doramectin.
Broad-spectrum: a single treatment with Dectomax Pour-On for Cattle effectively treats and controls a wide range of internal roundworms and arthropod parasites that impair the health and productivity of cattle.
Long-action: the sustained drug concentrations that result from its unique pharmacokinetics enable the product to protect cattle against parasite infection and reinfection for extended periods following treatment.
Safety: Dectomax Pour-On for Cattle has a wide margin of safety in all classes of cattle.
Its broad spectrum of activity, favorable pharmacokinetics and exceptional toleration make it an ideal product for application as an antiparasitic for cattle.

Uses
Dectomax Pour-On for Cattle is indicated for the treatment of the following harmful species of gastrointestinal roundworms, lungworms, eyeworms, warbles, sucking and biting lice, mange mites and hornfly in cattle.
Gastrointestinal roundworms (adults and fourth stage larvae)
Ostertagia ostertagi (including inhibited larvae)
O. lyrata1
Haemonchus placei
Trichostrongylus axei
T. colubriformis
Cooperia oncophora
C. punctata1
C. surnabada (syn. mcmasteri)1
Bunostomum phlebotomum1
Oesophagostomum radiatum
Trichuris spp1
1 adults only
Lungworms (adults and fourth stage larvae)
Dictyocaulus viviparus
Eyeworms (adults)
Thelazia spp
Warbles (parasitic stages)
Hypoderma bovis
H. lineatum
Biting lice
Damalinia (Bovicola) bovis
Sucking lice
Haematopinus eurysternus
Linognathus vituli
Solenopotes capillatus
Mange mites
Sarcoptes scabiei
Chorioptes bovis
Psoroptes bovis
Hornfly
Haematobia irritans
Duration of activity
Dectomax Pour-On protects cattle against infection or reinfection with the following parasites for the periods indicated.
<img src="images/dectomaxpour1.jpg">
Dectomax Pour-On for Cattle also controls horn flies (Haematobia irritans) for at least 42 days after treatment.
To obtain optimal benefit from the long-action of Dectomax Pour-On for Cattle, it is recommended that cattle which are set-stocked should be treated at turn-out and eight weeks later. Used in this way Dectomax Pour-On for Cattle will reduce the build-up of infective larvae on pasture and protect such animals from parasitic gastro-enteritis and parasitic bronchitis throughout the grazing season. To obtain these results, all animals should be included in the programme and untreated cattle must not be introduced to the pasture. Moreover, treatment with Dectomax Pour-On for Cattle at turn-out and eight weeks later may allow the development of naturally acquired immunity. However, due to the unpredictable nature of lungworm epidemiology, clinical signs of lungworm disease may on occasion be seen, particularly towards the end of the grazing season, if the season is long. If this occurs cattle should be further treated against lungworm.

Dosage and administration
Administer Dectomax Pour-On for Cattle topically at a dosage of 500 mcg doramectin per kilogram of bodyweight i.e. 1ml of solution / 10 kg bodyweight.

Administration
Dectomax Pour-On for Cattle should be applied topically along the mid-line of the back in a narrow strip between the withers and tailhead.
Directions for using the dosing cup (250 ml and 1 litre bottles only)
a Rotate the cup on the bottle neck until tight (so the spout is aligned at the mid point on the west side of the bottle).
b Select the dose:
Twist the dosing screw to the desired position, so that the correct number of mls is shown at the set dose mark.
The first complete turn of the dosing screw will set the dose at 10 ml (i.e. 100 kg bodyweight): `10' show on the screw at set dose mark. Each additional turn increases the dose in 5 ml increments (i.e. 50 kg bodyweight) up to 50 ml.
a Overfill the dosing cup by squeezing the bottle, until the level of liquid goes over the selected dose, then release the pressure. The liquid will automatically come down to the selected dose.
b Pour the product along the back of the animal.
When body weight is between weight markings on the dosing cup, use the higher dose volume.
Directions for using a pour-on applicator* (2.5, 3 and 5 litre backpack)
Connect the pour-on applicator to the backpack as follows:
Attach the open end of the draw-off tubing to the pour-on applicator.
Attach draw-off tubing to the cap with the stem. Replace shipping cap with the cap that has the draw-off tubing. Tighten the draw-off cap.
Gently prime the pour-on applicator, checking for leaks.
Follow manufacturer's directions for correct use and care of equipment.
* Applicators compatible with this formulation are available for use with Dectomax Pour-On for Cattle. Some applicators may be incompatible with this formulation.

Contra-indications, warnings, etc
Cattle must not be slaughtered for human consumption within 35 days of treatment.
Do not use in lactating cows used to produce milk for human consumption, or in dry cows or pregnant dairy heifers within 60 days prior to calving.
Do not use in dogs, as severe adverse reactions may occur.
For animal treatment only.
For external use only.
Keep out of reach of children.
Wash hands after use.
This product is to be applied to skin surface only.
Do not administer orally or parenterally.
Do not apply to areas of skin which are contaminated with mud or manure.
As is the case with similar products, in rare cases small skin lesions may occur at the administration site.
Dectomax Pour-On for Cattle may be irritating to human skin and eyes and users should be careful not to apply it to themselves or to other persons. Operators should wear rubber gloves and boots with a waterproof coat when applying the product. Protective clothing should be washed after use. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and get medical attention.
Do not smoke or eat while handling the product.
Highly Flammable - Keep away from heat, sparks, open flame or other sources of ignition.

Environmental Safety
Extremely dangerous to fish and aquatic life. Any unused materials, product or waste material should be disposed of in accordance with national requirements or in line with guidance from a local waste regulatory authority.

Pharmaceutical precautions
Do not store above 30°C. Do not refrigerate. Protect from light.
If stored at temperatures below 4°C Dectomax Pour-On for Cattle may appear cloudy. Allowing to warm at room temperature will restore the normal appearance without affecting efficacy.