Cydectin Injection 500ml | Moxidectin Injection sheep wormer-Hyperdrug

Presentation A sterile, clear to pale yellow, aqueous solution containing 1.0% w/v moxidectin (active substance); 4.0% w/v benzyl alcohol PhEur (solubiliser and antimicrobial preservative); 0.25% w/v butylated hydroxytoluene PhEur and 0.027% w/v disodium edetate PhEur (antioxidants). Uses Moxidectin is a second generation macrocyclic lactone of the milbemycin family. For the prevention and treatment of psoroptic mange (scab) in sheep For the treatment and control of infections caused by moxidectin sensitive strains of the following endoparasites and ectoparasites: Gastro-intestinal nematodes: •Haemonchus contortus •Ostertagia (Teladorsagia) circumcincta (including inhibited larvae) •Trichostrongylus axei (adults) •Trichostrongylus colubriformis (adults and L3) •Nematodirus spathiger (adults) •Cooperia curticei (adults) •Cooperia punctata (adults) •Gaigeria pachyscelis (L3) •Oesophagostomum columbianum (L3) •Chabertia ovina (adults) Respiratory tract nematode: •Dictyocaulus filaria Larvae of diptera: •Oestrus ovis (L1, L2, L3) Cydectin has a persistent effect in preventing infection or reinfection for: •at least 4 weeks against Psoroptes ovis •5 weeks against Ostertagia circumcincta and Haemonchus contortus •4 weeks against Gaigeria pachyscelis and Oesophagostomum columbianum •2 weeks against Trichostrongylus colubriformis. Trials have shown that Cydectin may be effective against strains of Haemonchus contortus resistant to benzimidazoles, ivermectin and doramectin. ROUTINE PREVENTION OF SCAB One injection at the recommended dosage will protect against Psoroptes ovis (scab mite) infestation for at least 28 days. TREATMENT OF SCAB OUTBREAKS Two injections at the recommended dosage, 10 days apart.

Dosage and administration Dosage: 0.1ml per 5kg liveweight to give 0.2mg moxidectin/kg liveweight. Administration: Inject subcutaneously (under the skin) in the neck. Use sterile 18 gauge needles or smaller, of half inch (1.5 cm) length. Ensure that the needle is inserted carefully under the skin using aseptic precautions and that product does not leak from the injection site. Be certain that the needle has penetrated the skin before delivering the dose. Determine sheep weight to ensure correct dosage is used. Check dose rates and equipment before injection commences. DO NOT UNDERDOSE. As with any scab treatment, underdosing can cause suppression and spread of the disease. When treating groups of animals, use only the Cydectin Automatic Injector and vented draw-off system. For treatment of individual sheep, a syringe not exceeding 2.5 ml and calibrated in increments of 0.1 ml should be used. Syringes must be filled from the vial through a dry, sterile draw-off needle that has been placed in the vial stopper. Vial stoppers must not be broached more than 10 times.

Contra-indications, warnings, etc
Not to be used in animals vaccinated against footrot.
Animals must not be slaughtered within 70 days of the last treatment.
Not for use in sheep producing milk for human consumption or industrial purposes, including the dry period.
For animal treatment only.
Do not smoke, eat or drink when using this product.
Wash hands after use.
Keep out of the reach of children.
Avoid direct contact with skin and eyes.
For subcutaneous use only.
Take care to avoid self-injection. If this occurs it is unlikely that any symptoms will be observed.
Advice to Medical Practitioners: in cases of accidental self-injection treat any specific signs symptomatically.
Read entire package insert before using this product.
Not to be mixed with other Veterinary Medicinal Products before administration.

Environmental safety
Cydectin may be toxic to fish and aquatic organisms. Do not contaminate ponds, waterways or ditches with product or used containers. Dispose of any unused product and empty containers in accordance with guidance from your local waste authority.

Pharmaceutical precautions
Do not store above 25oC.
Protect from light
Following withdrawal of the first dose, use the product within six months.
When the product is broached for the first time, the date on which any product remaining in the container should be calculated. A statement of in-use shelf life is given on the package insert. This discard date should be written in the space provided on the label.
Shelf life is 36 months from date of manufacture.

Legal category POM-VPS (previously PML). Packaging Quantities 50ml , 200ml and 500ml high density polyethylene containers. Further information Clinical trials have shown that there are no signs of pain after injection and no irritation at the injection site. Cydectin 1% Injectable Solution for Sheep has a wide margin of safety and symptoms of overdosage do not generally occur at less than 10 times the recommended dose. Extensive studies in laboratory animals and cattle have shown no adverse effects during pregnancy. Not to be used in animals vaccinated against footrot. There are no known interactions with other animal health products used routinely in sheep such as mineral supplements, fluke or worm treatments, or clostridial vaccines. PREVENTION AND TREATMENT OF SCAB Prevention of scab For routine prevention, all sheep in the flock must be injected once. A single injection with Cydectin will protect against sheep scab for at least 28 days from the time of treatment. If sheep come in contact with infected animals after that time, infestation can occur. All bought-in or returned animals should be treated and isolated for 12 days before mixing with the rest of the flock. Ensure adequate fencing between neighbouring flocks. It has been demonstrated that a single injection of all sheep in an area (with a double treatment of any clinically affected animals) is an effective alternative to routine autumn dipping to eradicate sheep scab. Treatment of Scab Outbreaks Inject all sheep in the affected flock or sub-flock, twice, 10 days apart. The two injections must be given on different sides of the neck. It is important to ensure that all in-contact sheep are treated. Sheep scab mites can remain infective off the animal, on fences, posts etc. for at least 16 days. Since Cydectin protects for at least 28 days (i.e. longer than the time for which scab mites can remain infective off the animal), treated sheep can be immediately turned back onto the same pasture after dosing. Since the effect of any injectable on scab mites is not immediate, contact between treated infected sheep and non-treated, non-infected sub-flocks must be avoided until at least 12 days after the last treatment.. TREATMENT AND CONTROL OF WORMS Dosing guidelines Cydectin is a member of the avermectin/milbemycin 3-AV class of anthelmintics. The advice of a veterinary surgeon should be sought in using Cydectin 1% Injectable Solution for Sheep in a dosing programme, to ensure correct diagnosis of the nematode infection present and to minimise the risk of developing resistance. Cydectin gives optimal pasture protection against stomach worms (Ostertagia and Haemonchus) with an 8 week dosing interval - i.e. 5 week protection against stomach worm, plus a 3 week interval from any re-infection to the presence of eggs in the dung. More frequent dosing may be required for the treatment and control of intestinal worms (eg Trichostrongylus and Cooperia spp) due to a less persistent effect against these species of nematode. The following may be used as a guide: Ewes: Treat at or around lambing to minimise the `spring rise`, then again pre-tupping, when rams should be treated also. After treatment, Cydectin continues to kill stomach worms picked up by the ewe for 5 weeks, thus substantially reducing pasture contamination. This `vacuum-cleaning` effect greatly reduces the worm challenge to lambs grazing the same pasture. Lambs: The first dose should be given at around 4-6 weeks of age, with a second dose, if required 8 weeks later. For treatment and control of winter Trichostrongylosis (Black Scour) dosing may need to be repeated at more frequent intervals due to a less persistent effect against intestinal nematodes. Nematodirus: For treatment and control of Nematodirus battus, use Cydectin 0.1% Oral Drench for sheep. Read package insert carefully before use. Marketing authorisation number Vm 01596/4257.

Cydectin Sheep Injection 500ml