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Corvental D for the treatment of bronchitis and congestive heart failure in the dog. Corvental-D Capsules are hard gelatin capsules containing either 100 mg, 200 mg or 500 mg Theophylline Ph.Eur. in a sustained release ``Divido' presentation.
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Corvental-D Capsules are hard gelatin capsules containing either 100 mg, 200 mg or 500 mg Theophylline Ph.Eur. in a sustained release ``Divido' presentation. The capsules are coloured and sized, according to active ingredient content
Corvental-D 100 mg: blue and white (small capsule)
Corvental-D 200 mg: green (small capsule)
Corvental-D 500 mg: green (large capsule)
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Dosage and administration
20 mg per kg bodyweight to be administered orally once daily.
Care should be taken to ensure that dogs are weighed carefully and accurately and the dose does not exceed 20 mg/kg bodyweight.
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Contra-indications, warnings, etc
Do not use in dogs with a known history of epileptiform seizures as convulsions have been reported in patients on theophylline treatment, often with no preceding signs of toxicity and in otherwise apparently normal animals.
Concurrent use of beta-sympathomimetics is contra-indicated, as additive or synergistic interactions resulting in exaggerated side effects may result.
Theophylline should be used with caution in patients with liver disease.
When theophylline is prescribed to pregnant bitches, the risk benefit of the treatment should be assessed. Only small amounts of theophylline are excreted in milk.
The following side effects have been reported; restlessness, agitation, excitement, vomiting, diarrhoea, polydipsia, sedation, reduced appetite and polyuria.
If vomiting occurs the dose should be reduced or the treatment discontinued.
If signs of CNS excitement occur (twitching, restlessness or convulsions) discontinue treatment immediately.
Plasma theophylline levels may increase in patients under treatment with macrolide and fluoroquinolone antibiotics such as erythromycin and enrofloxacin and decrease in patients receiving phenobarbitone or phenytoin.
Theophylline may reduce the convulsive threshold in patients receiving ketamine.
Administration of theophylline shortly before halothane anaesthesia may result in arrythmogenic effects.
In the case of accidental ingestion, seek medical advice immediately and show the package insert or the label to the physician.
For animal treatment only.
Keep out of reach of children.
Pharmaceutical precautions
Do not store above 30°C. Store in a dry place.
Disposal
Dispose of used packaging in the household refuse. Unused product should be returned to the veterinary surgeon.
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Legal category
POM-V
Packaging Quantities
Packs containing 60 capsules are available for all 3 strengths. The capsules are packed in blister strips.
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