Cobactan MC (pack of 30)

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Cobactan MC (pack of 30)


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Item Number: COBACTMC 
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Unit Price:

£83.99 (Incl. Vat)

Usually despatched within 24 hours

Quantity

NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Write the order number on the top of the prescription and post it to us.
  4. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free and is usually next working day but may take longer.
  5. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.

Can I send a faxed prescription or a photocopy?

No a prescription is a legal document which must be written according to UK regulations and signed and dated by a vet with UK registration. Photocopies or electronic copies are not valid.

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  2. Obtain a Prescription from your vet
  3. Write the order number on the top of the prescription and post it to us.

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As soon as your prescription is received your card will be charged and the medicine sent



Description

Cobactan MC (pack of 30).

Target species:
Lactating cows

Indications for use, specifying the target species:
For the treatment of clinical mastitis in the lactating dairy cow caused by bacteria susceptible to cefquinome

Contra-indications:
Not to be administered to animals which are known to be hypersensitive to cephalosporin antibiotics.
There may be cross sensitivity to penicillins.

Special warning for each target species:
None.

Special precautions for use:
Special precautions for use in animals:
None

Special precautions to be taken by the person administering the medicinal product to the animals:
When infusing heifers protective gloves should always be worn in order to avoid skin contact.


Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact.  Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa.  Allergic reactions to these substances may occasionally be serious.

1. Do not handle this product if you know you are sensitised, or if you have been advised not to work which such preparations.

2. Handle this product with great care to avoid exposure, taking all recommended precautions.

3. If you develop symptoms following exposure, such as skin rash, you should seek medical advice and show the Doctor this warning.  Swelling of the face, lips and eyes or difficulty in breathing are more serious symptoms and require urgent medical attention.

Wash hands after use.

Adverse reactions (frequency and seriousness):
None known.

Use during pregnancy or lactation:
The product is intended for use during lactation.  No restrictions apply for use during pregnancy.

Interaction with other medicinal products and other forms of interaction:
There is a cross sensitivity between the various cephalosporins.

Amounts to be administered and administration route:
The contents of one syringe should be infused gently into the teat of the infected quarter every 12 hours after each of three successive milkings.
Milk out the affected quarter(s).  After thoroughly cleaning and disinfecting the teat and teat orifice, gently infuse the contents of one syringe into each affected quarter.  Disperse the product by gentle massage of the teat and udder of the affected animal.

Further Information:
Combined Therapy
For the treatment of E.coli mastitis, experimental challenge studies have shown that the use of this product in combination with Cobactan 25 mg/ml suspension for injection leads to an improvement in efficacy, particularly in terms of bacterial cure rate.
 

For combined therapy the following treatment regime should be followed:

Cobactan 25 mg/ml Cobactan MC

1mg cefquinome/kg bw
(2ml/50 kg bw)

 

                24 hours

 

 

 

1mg cefquinome/kg bw
(2ml/50 kg bw)
 
One syringe gently infused into the teat of the infected quarter


                12 hours

One syringe gently infused into the teat of the infected quarter


                12 hours

One syringe gently infused into the teat of the infected quarter

Overdose (symptoms, emergency procedures, antidotes), if necessary:
No symptoms expected or emergency procedures required.

Withdrawal period(s):
 Animals must not be slaughtered for human consumption during treatment.  Cows may not be slaughtered for human consumption until 48 hours after the last treatment.

Milk must not be taken for human consumption during treatment.  Milk must be discarded for 84 hours (7 milkings if cows are milked twice daily) after the last treatment.  Milk may not be released for human consumption until 96 hours after the last treatment (at the 8th milking if cows are milked twice daily). With other milking routines, the basis of the veterinary surgeon's advice should be that milk may be taken for human consumption only after the same period from the last treatment.
For example, with three times a day milking, milk may be taken for human consumption only at the 12th milking.

When using Cobactan MC and Cobactan 25 mg/ml combination, animals must not be slaughtered for human consumption during treatment.  Cows may not be slaughtered for human consumption until 5 days after the last treatment.  Milk must not be taken for human consumption during treatment.  Milk must be discarded for 84 hours (7 milkings if cows are milked twice daily) after the last treatment.  Milk may not be released for human consumption until 96 hours after the last treatment (at the 8th milking if cows are milked twice daily).


PHARMACOLOGICAL PROPERTIES:
ATC Vet Code: QJ51DA92

Pharmacotherapeutic group: Antibacterials for intramammary use, Other
?-lactam antibacterials for intramammary use, Cephalosporins and related substances

Pharmacodynamic properties:
Cefquinome is an antibacterial drug of the cephalosporin group which acts by inhibition of cell wall synthesis. It is characterised by its broad therapeutic spectrum of activity and a high stability against penicillinases and beta-lactamases.

Pharmacokinetic particulars:
In vitro, Cefquinome has antibiotic activity against common Gram negative and Gram positive bacteria including Salmonella spp, Haemophilus spp, Pasteurella spp, Klebsiella spp, Corynebacterium pyogenes, Escherichia coli, A.pleuropneumoniae, Proteus mirabilis, Staphylococcus aureus, Streptococcus dysgalactiae and Streptococcus uberis.

The product has been developed to treat clinical mastitis caused by sensitive strains of Staphylococcus aureus, Streptococcus uberis, Streptococcus dysgalactiae, Escherichia coli and other enterobacteria.

The base disperses readily in milk and allows rapid distribution of Cefquinome.

Cefquinome as a fourth generation cephalosporin combines high cellular penetration and ß-lactamase stability. In contrast to cephalosporins of previous generations, cefquinome is not hydrolysed by chromosomally-encoded cephalosporinases of the Amp-C type or by plasmid mediated cephalosporinases of some enterobacterial species. However, some Extended Spectrum beta-lactamases (ESBL) can hydrolyse cefquinome and cephalosporins of other generations. The potential for resistance development against cefquinome is rather low. High-level resistance to cefquinome would require the coincidence of two genetic modifications, i.e. hyperproduction of specific ß-lactamases as well as decreased membrane permeability.

PHARMACEUTICAL PARTICULARS
List of excipients:
White soft paraffin
Liquid paraffin
 
Incompatibilities:
None known

Shelf life:
Shelf life of the veterinary medicinal product as packaged for sale: 30 months.

Special precautions for storage:
Do not store above 25°C
The syringe must only be used once.  Part used syringes should be discarded.

Nature and composition of immediate packaging:
White opaque polyethylene syringe containing 75mg cefquinome in packs of 3, 15, 20, 24 and 30 syringes.
Not all presentations may be marketed.

Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products, if appropriate:
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

Estimated " Usually shipped in" information is shown against most products

 

Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

Overseas orders

Postage outside of the UK is from £4.95

Finding out delivery Charges and options before checkout

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*Free delivery and selected charges on orders over £49.00 mainland UK Parcelforce Zone1 for more information check the delivery info page.
 
 

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