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Closamectin Pour On for Cattle |
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Closamectin cattle pour on is the first product of its kind to provide a 4-in-1 combination to effectively treat fluke, worms and lice in one easily applied pour-on solution. Allows farmers to apply a combination product containing both iveACrmectin and closantel to effectively treat cattle immature and mature flukes, as well as all of the major gastrointestinal roundworms of economic importance and both biting and sucking lice in cattle.
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Closamectin Pour On treats mixed trematode (liver fluke) and nematode or arthropod infestations due to roundworms, lungworms, eyeworms, warbles, mites and lice of cattle. Closamectin Pour On is a clear, blue/green, ready-to-use solution containing: 5mg/ml Ivermectin 200mg/ml Closantel.
For the treatment of mixed trematode (fluke) and nematode or arthropod infestations due to gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and lice of cattle. Gastrointestinal roundworms (adults and 4th stage larvae): Ostertagia ostertagi (including inhibited O. ostertagi), Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia spp., Oesophagostomum radiatum, Nematodirus helvetianus (adult), Strongyloides papillosus (adult). Lungworms (adult and 4th stage larvae): Dictyocaulus viviparus Trematodes (adult and late immatures): Fasciola gigantica, Fasciola hepatica Treatment of fluke at 12 weeks (mature) >95% efficacy. Treatment of fluke at 7 weeks (late immature) >95% efficacy.
Eyeworms (adult): Thelazia spp. Cattle grubs (parasitic stages): Hypoderma bovis, Hypoderma lineatum Lice: Linognathus vituli, Haematopinus eurysternus, Damalinia bovis Mange Mites: Chorioptes bovis,, Sarcoptes scabiei var bovis
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Closamectin Pour On should be administered topically at a dosage rate of 500 µg ivermectin per kg bodyweight and 20 mg closantel per kg bodyweight (1ml per 10kg). The formulation should be applied along the midline of the back in a narrow strip between the withers and the tail head. Assess bodyweight carefully prior to administration. The timing for treatment should be based on epidemiological factors and should be customised for each individual farm. A dosing programme should be established by a veterinary professional. If animals are to be treated collectively, rather than individually they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over-dosing.
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Animals must not be slaughtered for human consumption during treatment. Cattle must not be treated within 28 days of slaughter for human consumption. Do not use in cattle producing milk for human consumption. Do not use in non-lactating dairy cows including pregnant heifers within 60 days of calving. Closamectin Pour-On can be administered to cattle (including dairy, beef/suckler cattle) at any stage of pregnancy or lactation provided that the milk is not intended for human consumption. Do not use in cases of known hypersensitivity to the active ingredients. Do not apply to areas of skin which have mange, scabs or other lesions or to areas contaminated with mud or manure. Avermectins may not be well tolerated in non-target species (cases of intolerance with fatal outcome are reported in dogs – especially Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles/tortoises).
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Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy. Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. Underdosing which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device. The effect of rain on the pour-on formulation at the time of and after application has not been investigated. For maximum effect animals should be kept indoors or undercover following treatment, when there is rain or an imminent risk of rain. Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g., Faecal Egg Count Reduction Test). Where the results of the tests strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to ivermectin has been reported in Cooperia spp in cattle. Therefore the use of this product should be based on local epidemiological information about the susceptibility of the Cooperia spp and recommendations on how to limit further selection for resistance to anthelmintics.
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