Butador 10mg/ml Solution for Injection for horses, dogs and cats

Butador 10mg/ml Solution for Injection for horses, dogs and cats


Be the first to review this item

Item Number: BUTADORI 
Phone orders quick webcode: 

Select Product Option

Select one of the options below, then click 'Buy Now'

10ml £81.25 Usually despatched within 24 hours
10ml (Pack of 5) £362.15 Usually despatched within 24 hours

Quantity

NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Write the order number on the top of the prescription and post it to us.
  4. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free and is usually next working day but may take longer.
  5. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.

Can I send a faxed prescription or a photocopy?

No a prescription is a legal document which must be written according to UK regulations and signed and dated by a vet with UK registration. Photocopies or electronic copies are not valid.

X

The item you are adding to your basket requires a prescription before we can send the item to you but don't worry you can do this in 3 easy steps:

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Write the order number on the top of the prescription and post it to us.

 I have a prescription on file
 I am sending you a prescription in the post

As soon as your prescription is received your card will be charged and the medicine sent



Description

Butador 10mg/ml Solution for Injection for horses, dogs and cats 10ml.

Uses
HORSE
As an analgesic: For the short term relief of pain such as colic of gastrointestinal tract origin.
As a sedative and pre-anaesthetic: In combination with a2-adrenoceptor agonists (detomidine, romifidine, xylazine): For therapeutic and diagnostic procedures such as minor standing surgery and sedation of intractable patients.
DOG/CAT
As an analgesic: For relief of moderate visceral pain e.g. pre- and post-surgical as well as post-traumatic pain.
As a sedative: In combination with a2-adrenoceptor agonists (medetomidine).
As a pre-anaesthetic: Part of anaesthetic regime (medetomidine, ketamine).

Dosage and administration
Horse: Intravenous use
Dog: Intravenous, subcutaneous and intramuscular use
Cat: Intravenous and subcutaneous use

HORSE
As an analgesic
Monotherapy:
0.1 mg/kg (1 ml/100 kg bw) IV.
As a sedative and as a pre-anaesthetic
With detomidine:
Detomidine: 0.012 mg/kg IV, followed within 5 minutes by
Butorphanol: 0.025 mg/kg (0.25 ml /100 kg bw) IV.
With romifidine:
Romifidine: 0.05 mg/kg IV, followed within 5 minutes by
Butorphanol: 0.02 mg/kg (0.2 ml/100 kg bw) IV.
With xylazine:
Xylazine: 0.5 mg/kg IV, followed after 3-5 minutes by
Butorphanol: 0.05–0.1 mg/kg (0.5-1 ml/100 kg bw) IV.
DOG
As an analgesic
Monotherapy:
0.1 - 0.4 mg/kg (0.01 – 0.04 ml/kg bw) slowly IV (in the lower to medium dose range) as well as IM, SC.
For post-operative pain control the injection should be administered 15 minutes before the end of anaesthesia in order to achieve sufficient pain relief during the recovery phase.
As a sedative
With medetomidine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IV, IM
Medetomidine: 0.01 mg/kg IV, IM.
As a pre-anaesthetic
With medetomidine and ketamine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IM
Medetomidine: 0.025 mg/kg IM, followed after 15 minutes by
Ketamine: 5 mg/kg IM.
It is only possible to use atipamezole 0.1 mg/kg body weight for medetomidine-antagonisation when ketamine action has ceased.
CAT
As an analgesic
Monotherapy:
15 minutes prior to recovery either: 0.4 mg/kg (0.04 ml/kg bw) SC or: 0.1 mg/kg (0.01 ml/kg bw) IV
As a sedative
With medetomidine:
Butorphanol: 0.4 mg/kg (0.04 ml/kg bw) SC
Medetomidine: 0.05 mg/kg SC.
For wound debridement an additional local anaesthesia is recommended.
Medetomidine-antagonisation is possible with atipamezole 0.125 mg/kg body weight.
As a pre-anaesthetic
With medetomidine and ketamine:
Butorphanol: 0.1 mg/kg (0.01 ml/kg bw) IV
Medetomidine: 0.04 mg/kg IV
Ketamine: 1.5 mg/kg IV.
It is only possible to use atipamezole 0.1 mg/kg body weight for medetomidine–antagonisation when ketamine action has ceased.
Butorphanol is intended for use where short (horse and dog) and short to medium (cat) analgesia is required. The dose may be repeated as required. The need for and timing of repeated treatment will be based on clinical response. For information on the duration of analgesia see section “Further information”.
Rapid intravenous injection should be avoided.
Do not mix the product with other veterinary medicinal products in one syringe.

Contra-indications, warnings, etc
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not use for treatment of animals with severe dysfunction of the liver and kidneys, in case of cerebral injury or organic brain lesions and in animals with obstructive respiratory diseases, heart dysfunctions or spastic conditions.
For combination use with a2-agonists in horses:
Do not use in horses with a pre-existing cardiac dysrhythmia. The combination will cause a reduction in gastrointestinal motility and consequently should not be used in cases of colic associated with impaction. Do not use combination during pregnancy.

Adverse reaction
HORSE
Undesirable effects are generally related to the known activity of opioids. In published trials with butorphanol, transient ataxia, lasting about 3 to 15 minutes, occurred in about 20 % of horses. Mild sedation occurred in about 10 % of horses. Increased motor activity (running movements) is possible.
Gastrointestinal motility may be reduced.

For combination use:
Any reduction of gastrointestinal motility caused by butorphanol may be enhanced by the concomitant use of a2-agonists. The respiratory depressive effects of a2-agonists may be enhanced by concomitant butorphanol, particularly if respiratory function is already impaired. Other undesirable effects (e.g. cardiovascular) are likely to be related to the a 2-agonist.

DOG/CAT
Depression of the respiratory and cardiovascular system. Local pain associated with intramuscular administration. Decreased gastrointestinal motility. In rare cases, ataxia, anorexia and diarrhoea. In cats excitation or sedation, anxiety, disorientation, dysphoria and mydriasis are possible.
If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

Special warnings
The precautionary measures required for contact with animals should be followed and stress factors for the animals should be avoided.
In cats, individual response to butorphanol may be variable. In the absence of an adequate analgesic response, an alternative analgesic agent should be used.
Increasing of the dose may not increase the intensity or duration of analgesia.

Special precautions for use in animals
The safety of the product in puppies, kitten and foals has not been established. Use of the product in these groups should be on the basis of a risk-benefit analysis by the responsible veterinarian.
Due to its antitussive properties, butorphanol may lead to an accumulation of mucous in the respiratory tract. Therefore, in animals with respiratory diseases associated with increased mucous production, butorphaol should only be used after a risk-benefit evaluation by the responsible veterinarian. If respiratory depression occurs, naloxone may be used as an antidote.
Sedation may be noted in treated animals. The combination of butorphanol and a2-adrenoceptor agonists should be used with caution in animals with cardiovascular disease. The concurrent use of anticholinergic drugs e.g atropine should be considered.
Administration of butorphanol and romifidine in one syringe should be avoided due to increased bradycardia, heart block and ataxia.

HORSE
The use of the product at the recommended dose may lead to transient ataxia and/or excitement. Therefore, to prevent injuries in patient and people when treating horses, the location for the treatment should be chosen carefully.

CAT
Cats should be weighed to ensure that the correct dose is calculated. An appropriate graduated syringe must be used to allow accurate administration of the required dose volume (e.g. insulin syringe or 1 ml graduated syringe). If repeated administrations are required, use different injection sites.
Interaction with other medicinal products
The concomitant administration of other drugs which are metabolised in the liver may enhance the effect of butorphanol.
Butorphanol used with concurrently administered anaesthetics, centrally sedative or respiratory depressive drugs produces additive effects. Any use of butorphanol in this context requires acute control and a careful adaptation of the dose.
Administration of butorphanol may remove the analgesic effect in animals, which have already received pure µ-opioid analgesics.

Overdose
HORSE
Increased dosages could result in respiratory depression as a general opioid effect. Intravenous doses of 1.0 mg/kg (10 x the recommended dose), repeated at 4-hourly intervals for 2 days, led to transient adverse effects, including pyrexia, tachypnoea, CNS signs (hyperexcitability, restlessness, mild ataxia leading to somnolence) and gastrointestinal hypomotility, sometimes with abdominal discomfort. An opioid antagonist (e.g. Naloxone) may be used as an antidote.

DOG/CAT
Miosis (dog)/Mydriasis (cat), respiratory depression, hypotension, disorders of the cardiovascular system and in severe cases respiratory inhibition, shock and coma. Depending on the clinical situation counter-measures should be taken under intense medical monitoring. Monitoring is required for a minimum of 24 hours.

Use during pregnancy and lactation
Butorphanol crosses the placental barrier and penetrates into milk. Studies in laboratory species have not produced any evidence of teratogenic effects.
The safety of this veterinary medicinal product has not been established in the target species during pregnancy and lactation. The use of butorphanol during pregnancy and lactation is not recommended.

User warnings
Butorphanol has opioid-like activity. Precautions should be taken to avoid accidental injection/self-injection with this potent drug. The most frequent adverse effects of butorphanol in humans are drowsiness, sweating, nausea, dizziness and vertigo and may occur following unintended self-injection. If accidental self-injection occurs, seek medical advice immediately and show the package leaflet or the label to the physician. Do not drive. An opioid antagonist (e.g. naloxone) may be used as an antidote. Wash splashes from skin and eyes immediately

Withdrawal period
Horse (meat & offal): Zero days

Pharmaceutical precautions
Keep out of the sight and reach of children.
This veterinary medicinal product does not require any special temperature storage conditions. Keep the vial in the outer carton in order to protect from light.
Do not use after the expiry date stated on the label. Shelf-life after first opening the immediate container: 28 days

Legal category
Legal category: POM-V

Packaging quantities
1 x 10 ml, 5 x 10 ml, 10 x 10 ml, 1 x 50 ml.
Not all pack sizes may be marketed.
 

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

Estimated " Usually shipped in" information is shown against most products

 

Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

Overseas orders

Postage outside of the UK is from £4.95

Finding out delivery Charges and options before checkout

  1. Simply add an item to your basket
  2. Click view basket/Cart
  3. Click estimate shipping charges
*Free delivery and selected charges on orders over £49.00 mainland UK Parcelforce Zone1 for more information check the delivery info page.
 
 

Reviews

Click here for the product datasheet