ACP Tablets-Hyperdrug

Presentation ACP Tablets 10 mg are pale yellow in colour and contain Acepromazine Maleate BP (Vet) equivalent to 10 mg acepromazine base. ACP Tablets 25 mg are pale yellow in colour and contain Acepromazine Maleate BP (Vet) equivalent to 25 mg acepromazine base. Uses The tablets are intended for use only in cats and dogs. Anaesthetic premedication Following acepromazine administration, the amount of anaesthetic necessary to induce anaesthesia is considerably reduced. This reduction is approximately one-third of a suitable induction agent. Tranquillisation Acepromazine tranquillisation (ataraxy) involves a modification of temperament which is not associated with hypnosis, narcosis or marked sedation. This is achieved with low doses of acepromazine. Sedation At higher dose rates acepromazine is a sedative. Travel sickness A dose of 1 mg per kg given orally a quarter to half an hour before a light meal is effective in the prevention of travel sickness. Idiopathic vomiting may be controlled by acepromazine. Acepromazine possesses anti-emetic, hypothermic, hypotensive and anti-spasmodic properties and shows a marked potentiating effect on barbiturate anaesthesia. Dosage and administration 0.25–3 mg per kg bodyweight by oral administration. Onset of effects will be observed after 10–15 minutes. Normally single doses of acepromazine are administered. Long term use is not recommended. Contra-indications, warnings, etc Acepromazine is hypotensive. Particular care should therefore be taken in hypovolaemic animals; rehydration should precede acepromazine administration. In some dogs, particularly Boxers and other short-nosed breeds, spontaneous fainting or syncope may occur due to sinoatrial block caused by excessive vagal tone, and an attack may be precipitated by acepromazine. Where there is a history of this type of syncope, or if it is suspected because of excessive sinus arrhythmia, it may be advantageous to control the dysrhythmia with atropine given just before the acepromazine. Large breeds It has been noted that large breeds of dog are particularly sensitive to acepromazine and the minimum dose possible should be used in these breeds. Overdosage Slow intravenous injection of norepinephrine (noradrenaline) should be used whenever a hypertensive agent is required to reverse any fall in blood pressure. Epinephrine (adrenaline) is contra-indicated in the treatment of acute hypotension produced by overdosage of acepromazine maleate, since further depression of systemic blood pressure can result. Other pressoramines such as norepinephrine or neosynephrine should be administered to reverse hypotensive effects. However, the reversing effect of norepinephrine is likely to be transient and repeated doses will normally be required. Not for use in pregnant animals. For animal treatment only. Wash hands after use. In the event of accidental ingestion seek medical advice taking this warning to show your doctor. Pharmaceutical precautions Do not store above 25°C. Protect from light. Keep out of reach of children. Disposal Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority. Packaging Quantities Containers of 500 × 10 mg or 25 mg tablets. Legal category POM-V (previously POM). Further information Nil.

ACP Tablets 10 mg are pale yellow in colour and contain Acepromazine Maleate BP (Vet) equivalent to 10 mg acepromazine base. ACP Tablets 25 mg are pale yellow in colour and contain Acepromazine Maleate BP (Vet) equivalent to 25 mg acepromazine base. Uses The tablets are intended for use only in cats and dogs. Anaesthetic premedication Following acepromazine administration, the amount of anaesthetic necessary to induce anaesthesia is considerably reduced. This reduction is approximately one-third of a suitable induction agent. Tranquillisation Acepromazine tranquillisation (ataraxy) involves a modification of temperament which is not associated with hypnosis, narcosis or marked sedation. This is achieved with low doses of acepromazine. Sedation At higher dose rates acepromazine is a sedative. Travel sickness A dose of 1 mg per kg given orally a quarter to half an hour before a light meal is effective in the prevention of travel sickness. Idiopathic vomiting may be controlled by acepromazine. Acepromazine possesses anti-emetic, hypothermic, hypotensive and anti-spasmodic properties and shows a marked potentiating effect on barbiturate anaesthesia.

Contra-indications, warnings, etc Acepromazine is hypotensive. Particular care should therefore be taken in hypovolaemic animals; rehydration should precede acepromazine administration. In some dogs, particularly Boxers and other short-nosed breeds, spontaneous fainting or syncope may occur due to sinoatrial block caused by excessive vagal tone, and an attack may be precipitated by acepromazine. Where there is a history of this type of syncope, or if it is suspected because of excessive sinus arrhythmia, it may be advantageous to control the dysrhythmia with atropine given just before the acepromazine. Large breeds It has been noted that large breeds of dog are particularly sensitive to acepromazine and the minimum dose possible should be used in these breeds. Overdosage Slow intravenous injection of norepinephrine (noradrenaline) should be used whenever a hypertensive agent is required to reverse any fall in blood pressure. Epinephrine (adrenaline) is contra-indicated in the treatment of acute hypotension produced by overdosage of acepromazine maleate, since further depression of systemic blood pressure can result. Other pressoramines such as norepinephrine or neosynephrine should be administered to reverse hypotensive effects. However, the reversing effect of norepinephrine is likely to be transient and repeated doses will normally be required. Not for use in pregnant animals. For animal treatment only. Wash hands after use. In the event of accidental ingestion seek medical advice taking this warning to show your doctor. Pharmaceutical precautions Do not store above 25°C. Protect from light. Keep out of reach of children. Disposal Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.